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Synthesis of 5,5-Bis (p-methoxy-m-bromophenyl)-2-thiohydantoin Derivatives Author: Hung-Cheh Chiang, Pei-Lein Wang

Abstract：

Treatment of 5,5-bis (p-methoxy-m-bromophenyl)-2-thiohydantoin (2a) with methyl iodide in basic alcohol solution gave 5,5-bis (p-methoxy-m-bromo-phenyl)-2-methythiohydantoin (3a), in 81.0% yield, whose ten new derivatives (3b-3f), (4a-4e) were also prepared in a similar fashion.

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